I'll add my experience towing an enclosed car hauler for snowmobile trip with my 2020 3500 SO Mega cab. Truck had about 5500 miles on it when we left.
Miles: 2788
Gallons of Fuel: 320
Gallons of Def: 11
Fuel MPG: 8.70
DEF MPG: 253
Def to Fuel - 3.43%
Driving around town I think i get around 500-600 MPG for DEF
Miles: 2788
Gallons of Fuel: 320
Gallons of Def: 11
Fuel MPG: 8.70
DEF MPG: 253
Def to Fuel - 3.43%
Driving around town I think i get around 500-600 MPG for DEF