Looking on Cummins' website at the specs of the new 7.2L vs the old 6CT 8.3L that was used in Ford medium duties, the 7.2L is over 1600 lbs while the 6CT was just over 1500. I don't see the pickup getting an extra ~400-500 lbs of engine when payload capacity is already a big negative in many peoples' eyes. It'd also make the truck significantly more front-heavy.
They never put the 8.3 6CT in a pickup, and I don't see the 7.2L being any different.
That being said, I still view the late 90's 6CT F700/800 as one of the best trucks a guy could get. You could get a crew cab, air brakes, Allison 6 speed, air condition, 4x4. That option went away after the 90's and I've never seen the "big block" Cummins option offered in the "medium duty pickups" since. Even International shot themselves in the foot using the 6.0L powerjoke in the MXT instead of their DT466 (or even DT360). You look at the F450/550 or Silverado 4500 today and it's the same baby diesel that's in their respective 2500's.
Now a Sterling/Ram 4500/5500 with the 7.2L, widetrack, rear air, and a pickup bed could be game changing... Definitely don't see a 2500 or 3500 getting a 1600+ pound engine, though.