Might not even have to given how loose they come from the factoryyou can pull the fuse.
Definitely would like to explore this instead of pulling the fuse when the truck arrives.PAC audio ANC-CH01. The beauty of this thing is that it gives you anc bypass but also direct access to all the speaker wiring as well. So you can run the speaker lines to an LOC, amp or both and then route back into the factory speaker wires without ever messing with your factory wiring, you just cut and splice the wiring within the bypass cable. I am using it to plumb directly into an amp for a 12 inch sub under my back seat and likely later using a 4 channel amp to get way more power to my speakers and restore the bass roll off the factory deck puts out to protect the factory speakers.
Not only is it cheap and reversible, it just gives you a lot of options for manipulating stereo wiring without ever touching factory wires.Definitely would like to explore this instead of pulling the fuse when the truck arrives.